AI SaMD Playbook
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    Back to AI SaMD PlaybookPlanning tool · indicative numbers, not regulatory advice

    Submission cost & timeline estimator

    Pick a pathway. Get the user fee, the realistic prep window, the regulator review goal, and the deficiency-letter count you should budget for. Sources cited beside every number · update before you put any of this in a board deck.

    Government user fee
    $24,335
    Standard rate
    Regulator review (days)
    90 – 180
    12–26 weeks calendar time
    Deficiency letters expected
    1 – 3
    Plan response capacity for the high end
    Internal preparation
    4–9 months · estimated total prep + consultancy $97,340 – $292,020

    Includes V&V, clinical evidence assembly, cybersecurity documentation, PCCP drafting, eSTAR/eDocs build, and RA/QA cycles. Excludes clinical-trial costs and post-market surveillance build-out.

    Basis

    MDUFA V FY2026 fee schedule; FDA 510(k) decision goals; AI/ML lifecycle draft (Jan 2025).

    Notes

    Most AI 510(k)s receive at least one Additional Information request, often on validation data representativeness or PCCP scope.

    Indicative only · check the current published fee schedule before quoting.